BAFF Receptor, human recombinant, BioVisionSupplier: BioVision
4452-10 4452-50 4452-1000
10006-682EA 88.04 USD10006-682 10006-686 10006-684
BAFF Receptor, human recombinant, BioVision
Proteins and Peptides
>95% Pure active Recombinant human BAFF Receptor.
Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED₅₀ for this effect is typically 1-5 µg/ml in the presence of 1 µg/ml human soluble BAFF.
BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.