Caspase-5, human recombinant, BioVision

Supplier: BioVision

1085-25 1085-100
10004-958EA 225.61 USD
10004-958 10004-956
Caspase-5, human recombinant, BioVision
Enzymes
A cysteine protease involved in apoptosis 

Caspase-5 (also know as ICErelIII, TY) is a member of the caspase-family of cysteine proteases

The recombinant active human caspase-5 was expressed in E. coli. The active caspase-5 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-WEHD-pNA (Cat. #1102-200) or Ac-WEHD-AFC (1101-200).

Similar to other caspases, caspase-5 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active caspase-5 is a heterotetramer consisting of two large and two small subunits. To date the mechanism of caspase-5 activation and roles of caspase-5 in apoptosis are poorly understood.
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