IL-1 beta, rat recombinant, BioVision

Supplier: BioVision

4130-50 4130-1000 4130-10
10006-120EA 825.44 USD
10006-120 10006-118 10006-116
IL-1 beta, rat recombinant, BioVision
Proteins and Peptides
An important mediator of inflammatory responses

The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is <0.1 ng/ml, corresponding to a specific activity of >1 x 10⁷ units/mg.

IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, B-cell maturation and proliferation, mitogenic FGF-like activity and stimulation of the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.
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