Human Recombinant SCD30 Ligand (from CHO Cells)

Supplier: Tonbo Biosciences
21-7143-U100 21-7143-U500 21-7143-U050 21-7143-U010
10821-096EA 352.88 USD
10821-096 10821-098 10821-092 10821-094
Human Recombinant SCD30 Ligand (from CHO Cells)
CD30 ligand, also known as CD153 and TNFSF8, is a Type II glycoprotein and a member of the TNF superfamily. It is expressed on the surface of activated B cell subsets, T cells and monocytes. In the presence of CD30, CD30L is cleaved and the soluble form binds to CD30+ cells which can induce apoptosis in some cases. CD30L/CD30 interactions also generate signaling pathways leading to either cell death or proliferation. Studies suggest a role for CD30L/CD30 signaling in Th1, Th2 and Th17 responses, as well as in certain diseases such as allergic inflammation, rheumatoid arthritis and Hodgkin's lymphoma.
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