Recombinant Human sCD22 (Siglec-2) (Carrier-free), Tonbo BiosciencesSupplier: Tonbo Biosciences
21-7140-U020 21-7140-U005 21-7140-U500 21-7140-U100
10821-070EA 219.71 USD10821-070 10821-068 10821-074 10821-072
Recombinant Human sCD22 (Siglec-2) (Carrier-free), Tonbo Biosciences
Proteins and Peptides
sCD22, also known as Siglec-2 and BL-CAM, is a cell surface glycoprotein that is B-lineage restricted. It is expressed on the surface of mature B-cells and, to some extent, on immature B-cells. Siglec lectins belong to the immunoglobulin (Ig) superfamily. sCD22 is a coreceptor that binds the B-cell receptor (BCR) and acts as a negative regulator in B-cell receptor signal transduction. Loss of CD22 function may contribute to the pathogenesis of autoimmune diseases.