Recombinant Human PDGF-CC (Carrier-free), Tonbo BiosciencesSupplier: Tonbo Biosciences
21-7121-U100 21-7121-U005 21-7121-U500 21-7121-U020
10820-864EA 711.68 USD10820-864 10820-860 10820-866 10820-862
Recombinant Human PDGF-CC (Carrier-free), Tonbo Biosciences
Proteins and Peptides
Platelet-derived growth factor-CC (PDGF-CC) is one of the five dimeric proteins belonging to the PDGF family. Other members are homodimers PDGF-AA, PDGF-BB, PDGF-DD, and the heterodimer PDGF-AB. The PDGFs are produced by platelets, stored in platelet alpha-granules and are released upon platelet activation. PDGF proteins are generally considered as potent mitogens for connective tissue cells, and can also be chemotactic for fibroblasts, smooth muscle cells, neutrophils and mononuclear cells. PDGF-CC plays a role in angiogenesis, as well as cardiovascular development and function. Two receptors have been identified for the PDGF proteins - PDGFR alpha and PDGFR beta. PDGF-CC binds primarily to PDGFR alpha and activates PDGFR alpha homodimerization.