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Human Recombinant PDGF-CC (from E. coli)

Supplier: Tonbo Biosciences

Human Recombinant PDGF-CC (from <i>E. coli</i>)

Human Recombinant PDGF-CC (from <i>E. coli</i>)

21-7121-U100 21-7121-U005 21-7121-U500 21-7121-U020

10820-862EA 226.74 USD

10820-862 10820-860 10820-866 10820-864

Human Recombinant PDGF-CC (from E. coli)

Platelet-derived growth factor-CC (PDGF-CC) is one of the five dimeric proteins belonging to the PDGF family. Other members are homodimers PDGF-AA, PDGF-BB, PDGF-DD, and the heterodimer PDGF-AB. The PDGFs are produced by platelets, stored in platelet alpha-granules and are released upon platelet activation. PDGF proteins are generally considered as potent mitogens for connective tissue cells, and can also be chemotactic for fibroblasts, smooth muscle cells, neutrophils and mononuclear cells. PDGF-CC plays a role in angiogenesis, as well as cardiovascular development and function. Two receptors have been identified for the PDGF proteins - PDGFR alpha and PDGFR beta. PDGF-CC binds primarily to PDGFR alpha and activates PDGFR alpha homodimerization.

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