Human Recombinant DKK2 (from CHO Cells)

Supplier: Tonbo Biosciences
21-7101-U500 21-7101-U100 21-7101-U002 21-7101-U010
10820-718EA 226.74 USD
10820-718 10820-720 10820-722 10820-716
Human Recombinant DKK2 (from CHO Cells)
The DKK (Dickkopf) family of secreted proteins includes DKK-1 through -4, and a related protein, Soggy (DKK-11). Like DKK-1, DKK-2 can act as an antagonist of the Wnt signaling pathway, forming inhibitory complexes with Wnt co-receptor LRP6 and Kremen-2. However, when LRP6 is overexpressed direct binding of DKK-2 activates canonical Wnt signaling. DKK-2 is expressed in bone, eye and other mesenchymal tissues.
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