Mouse Recombinant CD40 Ligand (from E. coli)

Supplier: BioVision
4015-500
10005-430EA 2042.53 USD
10005-430
Mouse Recombinant CD40 Ligand (from E. coli)
A protein primarily expressed on activated T cells and involved in immune functions.

ED₅₀ is <0.1 μg/ml determined by its ability to induce TNF-α and MIP-1α production by murine splenocytes.

CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant murine CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.
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