The peptide precursor of calcitonin involved in calcium homeostasis.
Human Procalcitonin was tested using Biomerieux reagents on the Min-Vidas. The assay was run at 80 ng/ml with a recovery of 82 percent.
Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed Procalcitonin rise significantly after bacterial infection, trauma or shock. Recombinant Human Procalcitonin produced in E.coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids with a molecular weight of 12,796 Daltons.