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H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, Bachem

ANP/ANF is synthesized in cardiac myocytes and is primarily released in response to atrial wall stretching and intravascular volume expansion. The peptide signals via the guanylate cyclase-linked natriuretic peptide receptor A (NPR-A) and plays an important role in blood pressure regulation and blood volume homeostasis. ANP/ANF exerts vasodilatory, diuretic, natriuretic, anti-inflammatory, antifibrotic and antimitogenic effects. As BNP, ANP stimulates lipolysis in adipocytes. Millucci et al. studied the aggregation behavior of αANP, which may play a role in congestive heart failure.

  • Sequence: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
  • CAS-No.: 89213-87-6
  • Mol.weight: 3080.49
  • SumFormula: C₁₂₇H₂₀₃N₄₅O₃₉S₃
  • Bulk item no.: H-2095
  • Synonym(s): αhANF#Carperitide#Atrial Natriuretic Peptide (ANP) (1-28) alpha, canine, human, ovine
  • EINECS no.: -
  • MDL no.: MFCD00076226

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg H-2095.0500 H-2095.0500BA Each (500µG) Retrieving
1 mg H-2095.1000 H-2095.1000BA Each (1mg) Retrieving
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Protein/Peptide Name Atrial Natriuretic Factor 1-28
Species Human
CAS No. 89213-87-6
Molecular Weight 3080.49
Molecular Formula C₁₂₇H₂₀₃N₄₅O₃₉S₃
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Binding (Disulfide bond)
Peptide Atrial Natriuretic Factor 1-28
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