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H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gln-Asn-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH, Bachem

Supplier: BACHEM AMERICAS INC
H-7412.1000 H-7412.0500
Transgenic mice expressing the vasculotropic Dutch/Iowa (E693Q/D694N) mutant human Aβ precursor protein in brain (Tg-SwDI) accumulate abundant cerebral microvascular fibrillar amyloid deposits and exhibit robust neuroinflammation. In vitro, the doubly mutated Aβ peptides showed an increased propensity to fibrillation and pathogenicity compared to the Dutch and Iowa single mutants.

  • Sequence: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gln-Asn-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
  • CAS-No.: 374796-75-5
  • Mol.weight: 4327.90
  • SumFormula: C₁₉₄H₂₉₇N₅₅O₅₆S
  • Bulk item no.: H-7412
  • Synonym(s): Amyloid β-Protein (1-40) E22Q/D23N#Amyloid β-Protein (1-40) Dutch/Iowa Double Mutation
  • EINECS no.: -
  • MDL no.:




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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg H-7412.0500 10796-830 Each (500µG) Retrieving

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

1 mg H-7412.1000 10796-832 Each (1mg) Retrieving

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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SPECIFICATIONS

Protein/Peptide Name (Gln22/Asn23)-Amyloid B-Prot
Species Human
CAS No. 374796-75-5
Molecular Weight 4327.9
Molecular Formula C₁₉₄H₂₉₇N₅₅O₅₆S
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
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