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(ASN7)-AMYLOID B-PROTEIN (1-40), Bachem

The Tottori (D7N) mutation of β-amyloid peptides accelerates fibrillation without increasing protofibril formation. Ono et al. showed that the English and Tottori mutations alter Abeta assembly at its earliest stages, monomer folding and oligomerization, and produce oligomers that are more toxic to cultured neuronal cells than are wild type oligomers.

  • Sequence: H-Asp-Ala-Glu-Phe-Arg-His-Asn-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
  • Mol.weight: 4328.88
  • SumFormula: C₁₉₄H₂₉₆N₅₄O₅₇S
  • Bulk item no.: H-7334
  • Synonym(s): Amyloid β-Protein (1-40) Tottori Mutation#Amyloid β-Protein (1-40) D7N

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg H-7334.0500 H-7334.0500BA Each (1mg) Retrieving
1 mg H-7334.1000 H-7334.1000BA Each (1mg) Retrieving
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Protein/Peptide Name (Asn7)-beta-Amyloid (1-40)
Molecular Weight 4328.88
Molecular Formula C₁₉₄H₂₉₆N₅₄O₅₇S
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Peptide (Asn7)-beta-Amyloid (1-40)
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