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Anti-SYNGAP Rabbit Polyclonal Antibody

Supplier: Bioss

The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: SYNGAP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BS-10392R 10243-140 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name Synaptic Ras GTPase-activating protein 1
Antigen Symbol SYNGAP
Antigen Synonyms synaptic Ras GTPase activating protein 1 homolog, neuronal RasGAP, MRD5, ras GTPase-activating protein SynGAP, KIAA1938, synaptic Ras GTPase activating protein 1, SYNGAP1, DKFZp761G1421, RASA5, RASA1
Clonality Polyclonal
Concentration 1 μg/μl
Conjugation Unconjugated
Cross Adsorption No
Form liquid
Gene ID 8831
Host Rabbit
ImmunoChemistry Yes
Isotype IgG
Modification Ser836
Purification Purified by Protein A
Reactivity Mouse, Rat, Human
Shipping Temperature 4°C
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Western Blot Yes
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