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Anti-Syntrophin-1+2+3 Rabbit Polyclonal Antibody

Supplier: Bioss
Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: Syntrophin-1+2+3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BS-10382R 10365-998 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol Syntrophin-1+2+3
Antigen Name Syntrophin-1+2+3
Reactivity Rat, Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms SNTB1_HUMAN, Syntrophin alpha 1, SNTA1_HUMAN, SNTB1, SNT2, Syntrophin-1, Syntrophin-3, Beta-1-syntrophin, SNTB2_HUMAN, Syntrophin-2, SNT3, alpha-1-syntrophin, 59kDa dystrophin-associated protein A1 basic component 2, Syntrophin beta 1, SNT1, Syntrophin beta 2., SNTA1, Beta-2-syntrophin, SNTB2
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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