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Anti-PDK4 Rabbit Polyclonal Antibody

Supplier: Bioss

Pdk4 (pyruvate dehydrogenase kinase, isozyme 4) mediates glucose oxidation through inhibitory phosphorylation of the pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex (PDC) is a mitochondrial matrix enzyme that plays an key role in aerobic energy metabolism by catalyzing the oxidative decarboxylation of pyruvate to form acetyl-CoA for subsequent breakdown in the Krebs cycle. The enzymatic activity of the mammalian PDC is regulated through phosphorylation and desphosphorylation of the E1?subunit of the complex. The enzymes responsible for the phosphorylation and inactivation of the PDC are pyruvate dehydrogenase kinases (PDK1-4). [TISSUE SPECI FICITY] Ubiquitous; highest levels of expression in heart and skeletal muscle. Belongs to the PDK/BCKDK protein kinase family. Contains 1 histidine kinase domain.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: PDK4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BS-0682R 10239-868 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name Pyruvate Dehydrogenase Kinase 4
Antigen Symbol PDK4
Antigen Synonyms FLJ40832, Pyruvate dehydrogenase kinase isozyme 4 mitochondrial., Pyruvate dehydrogenase kinase isoform 4, Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial, Pyruvate dehydrogenase kinase 4
Clonality Polyclonal
Concentration 1 μg/μl
Conjugation Unconjugated
Cross Adsorption No
Form liquid
Gene ID 5166
Host Rabbit
ImmunoChemistry Yes
Isotype IgG
Purification Purified by Protein A
Reactivity Mouse, Rat, Human
Shipping Temperature 4°C
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Western Blot Yes
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