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Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody

Supplier: Bioss
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: Estrogen Receptor alpha + beta
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BS-0174R 10232-596 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol Estrogen Receptor alpha + beta
Antigen Name Estrogen Receptor alpha + beta
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms ERbeta, NR3A2, Erb, Erb2, Estradiol receptor, Estrogen receptor, Estra, Myocardial infarction, Atherosclerosis, Estr, OTTHUMP00000017718, NR3A1, Nuclear receptor subfamily 3 group A member 2, ER, Estrogen Receptor alpha/beta, ESTRB, ESR2, ER-alpha, Estrogen receptor beta 4, ER[b], HDL cholesterol, ESR BETA, ESRA, Estrogen Receptor 1, ER[a], Nuclear receptor subfamily 3 group A member 1, Estrogen receptor 1 alpha, Estrogen Receptor 2, ERalpha, ER Beta, ER Alpha, Estradiol Receptor alpha, included, RNESTROR., ESR1_HUMAN, Estrogen receptor 2 ER beta, susceptibility to, Era, DKFZp686N23123, ER-beta, Estrogen resistance, Estrogen receptor alpha, to hormone replacement, augmented response of, Estradiol Receptor beta, ESR1, ESR, OTTHUMP00000017719, ESRB
Gene ID 2099, 2100
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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