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Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody

Supplier: Bioss

The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: Estrogen Receptor alpha + beta
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BS-0174R 10232-596 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name Estrogen Receptor alpha + beta
Antigen Symbol Estrogen Receptor alpha + beta
Antigen Synonyms ERbeta, NR3A2, Erb, Erb2, Estradiol receptor, Estrogen receptor, Estra, Myocardial infarction, Atherosclerosis, Estr, OTTHUMP00000017718, NR3A1, Nuclear receptor subfamily 3 group A member 2, ER, Estrogen Receptor alpha/beta, ESTRB, ESR2, ER-alpha, Estrogen receptor beta 4, ER[b], HDL cholesterol, ESR BETA, ESRA, Estrogen Receptor 1, ER[a], Nuclear receptor subfamily 3 group A member 1, Estrogen receptor 1 alpha, Estrogen Receptor 2, ERalpha, ER Beta, ER Alpha, Estradiol Receptor alpha, included, RNESTROR., ESR1_HUMAN, Estrogen receptor 2 ER beta, susceptibility to, Era, DKFZp686N23123, ER-beta, Estrogen resistance, Estrogen receptor alpha, to hormone replacement, augmented response of, Estradiol Receptor beta, ESR1, ESR, OTTHUMP00000017719, ESRB
Clonality Polyclonal
Concentration 1 μg/μl
Conjugation Unconjugated
Cross Adsorption No
Form liquid
Gene ID 2099, 2100
Host Rabbit
ImmunoChemistry Yes
Isotype IgG
Purification Purified by Protein A
Reactivity Human, Mouse, Rat
Shipping Temperature 4°C
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Western Blot Yes
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