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Anti-ANKRD50 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD50 (ankyrin repeat domain 50) is a 1,429 amino acid phosphoprotein that contains nineteen ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and mosquito, ANKRD50 is encoded by a gene that maps to human chromosome 4q28.1. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which encodes an expanded glutamine tract in cases of Huntington's disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also linked to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ANKRD50
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9751R-CY7 10496-498 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol ANKRD50
Antigen Name Ankyrin Repeat Domain 50
Reactivity Mouse, Human, Rat
Conjugation Cy7®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Gene ID 57182
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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