Anti-FASP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

BS-9738R-A350
10492-988EA 792.04 USD
10492-988
Anti-FASP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antibodies
Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FASP1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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