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Anti-BLNK Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: BLNK
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9687R-CY3 10494-516 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol BLNK
Antigen Name B-cell linker
Reactivity Rat, Mouse, Human
Conjugation Cy3®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms Src homology 2 domain-containing leukocyte protein of 65 kDa, B-cell activation, B-cell adapter containing a SH2 domain protein, AGM4, BLNK-S, B-cell linker protein, bca, SLP-65, B cell adaptor containing SH2 domain, Src homology [SH2] domain-containing leukocyte protein of 65 kD, B-cell adapter containing a Src homology 2 domain protein, B cell linker protein, BASH, SLP65, cytoplasmic adapter protein, LY57
Gene ID 29760
Modification phospho-Tyr84
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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