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Anti-BLNK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss
BS-9687R-A647
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: BLNK
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat


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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9687R-A647 10494-512 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol BLNK
Antigen Name B-cell linker
Reactivity Human, Rat, Mouse
Conjugation Alexa Fluor® 647
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms LY57, B-cell linker protein, B-cell activation, B cell adaptor containing SH2 domain, bca, SLP-65, AGM4, BASH, Src homology 2 domain-containing leukocyte protein of 65 kDa, cytoplasmic adapter protein, B-cell adapter containing a Src homology 2 domain protein, Src homology [SH2] domain-containing leukocyte protein of 65 kD, B cell linker protein, SLP65, BLNK-S, B-cell adapter containing a SH2 domain protein
Gene ID 29760
Modification phospho-Tyr84
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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