Anti-MYLIP Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

BS-9674R-CY7
10494-304EA 792.04 USD
10494-304
Anti-MYLIP Rabbit Polyclonal Antibody (Cy7®)
Antibodies
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: MYLIP
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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