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Anti-MYLIP Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: MYLIP
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9674R-CY5 10494-300 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol MYLIP
Antigen Name Myosin Regulatory Light Chain Interacting Protein
Reactivity Mouse, Human, Rat
Conjugation Cy5®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor, MIR, inducible degrader of the LDL-receptor, E3 ubiquitin-protein ligase MYLIP, band 4.1 superfamily member BZF1, myosin regulatory lig, IDOL, cellular modulator of immune recognition (c-MIR)
Gene ID 29116
Concentration 1 μg/μl
Cross Adsorption No
Immunogen 65-103/445
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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