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Anti-IDH1 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
BS-9634R-CY5.5
The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ?ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ?ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: IDH1
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9634R-CY5.5 10493-690 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol IDH1
Antigen Name Isocitrate dehydrogenase [NADP] cytoplasmic
Reactivity Human, Rat, Mouse
Conjugation Cy5.5®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms IDH1, oxalosuccinate decarboxylase, NADP+-specific ICDH, peroxisomal, PICD, IDH, IDPC, isocitrate dehydrogenase 1 (NADP+), OTTHUMP00000206465, IDCD, OTTHUMP00000206466, NADP-dependent isocitrate dehydrogenase, IDP, OTTHUMP00000206464, cytosolic, soluble
Gene ID 3417
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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