Anti-RPE65 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

BS-9575R-CY5
10491-732EA 792.04 USD
10491-732
Anti-RPE65 Rabbit Polyclonal Antibody (Cy5®)
Antibodies
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: RPE65
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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