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Anti-RPE65 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss
BS-9575R-A488
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: RPE65
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9575R-A488 10491-722 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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SPECIFICATIONS

Antigen Symbol RPE65
Antigen Name Retinal Pigment Epithelium-specific 65 kDa protein
Reactivity Human, Rat, Mouse
Conjugation Alexa Fluor® 488
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms rd12, p63, retinoid isomerohydrolase, retinitis pigmentosa 20 (autosomal recessive), sRPE65, LCA2, retinol isomerase, RBP-binding membrane protein, retinal pigment epithelium-specific 65 kDa protein, RP20, mRPE65, all-trans-retinyl-palmitate hydrolase
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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