Anti-FFAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

BS-9564R-A350
10491-562EA 592.02 USD
10491-562
Anti-FFAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GPR40
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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