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Anti-FNTA Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss
BS-9547R-A350
FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PGGT1A
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-9547R-A350 10491-204 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol FNTA
Antigen Name Farnesyltransferase, CAAX Box, Alpha
Reactivity Mouse, Human, Rat
Conjugation Alexa Fluor® 350
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms Ras proteins prenyltransferase alpha, CAAX farnesyltransferase subunit alpha, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FTase-alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha
Gene ID 2339
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at -20°C for 12 months
Shipping Temperature 4°C
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