Anti-FBXO36 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-8470R-A647
10485-310EA 792.04 USD
10485-310
Anti-FBXO36 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antibodies
FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FBXO36
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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