Anti-VRK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-7706R-A647
10467-682EA 792.04 USD
10467-682
Anti-VRK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antibodies
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: VRK1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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