Anti-FLI1 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
BS-7662R-CY5.5
10467-302EA 642.06 USD
10467-302
Anti-FLI1 Rabbit Polyclonal Antibody (Cy5.5®)
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.Involvement in diseaseDefects in FLI1 are a cause of Ewing sarcoma (ES) . A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=A chromosomal aberration involving FLI1 is found in patients with Erwing sarcoma. Translocation t(11;22)(q24;q12) with EWSR1.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FLI1
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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