Anti-CIDEA Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

BS-7649R-A350
10466-552EA 792.04 USD
10466-552
Anti-CIDEA Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antibodies
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICARD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B (for cell death inducing DFF like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE A is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE A is expressed in many tissues.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CIDEA
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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