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Anti-GLA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss

BS-7593R-A555

10465-366EA 792.04 USD

10465-366

Anti-GLA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Antibodies

Galactosidase alpha is involved in the hydrolysis of terminal, non reducing alpha D galactose residues in alpha D galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase. Defects in GLA are the cause of Fabry's disease (FD). FD is a rare X-linked sphingolipidosis disease where glycolipid accumulates in many tissues. Clinical recognition in males results from characteristic skin lesions (angiokeratomas) over the lower trunk. Patients may show ocular deposits, febrile episodes, and burning pain in the extremities. Death results from renal failure, cardiac or cerebral complications of hypertension or other vascular disease. Heterozygous females may exhibit the disorder in an attenuated form, they are more likely to show corneal opacities.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: Galactosidase alpha
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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