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Anti-KLK6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-5870R-A647

10425-486EA 792.07 USD

10425-486

Anti-KLK6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Antibodies

Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: KLK6
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat

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