Anti-CASP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

BS-5802R-A488
10423-902EA 811.1 USD
10423-902
Anti-CASP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CASP2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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