Anti-ITGAV Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Supplier: Bioss

BS-5791R-FITC
10423-662EA 811.1 USD
10423-662
Anti-ITGAV Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Antibodies
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ITGAV
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host:
Isotype:
Reactivity:
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