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Anti-ARHGAP24 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-5785R-A647

10423-514EA 811.1 USD

10423-514

Anti-ARHGAP24 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Antibodies

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ARHGAP24
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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