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Anti-PDGFRB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

BS-5554R-A350

10418-988EA 746.43 USD

10418-988

Anti-PDGFRB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Antibodies

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PDGFRB
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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