Anti-MBP Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
BS-5475R-CY5.5
10418-408EA 757.83 USD
10418-408
Anti-MBP Rabbit Polyclonal Antibody (Cy5.5®)
Antibodies
Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: MBP
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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