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Anti-G6PDH Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss

BS-4974R-A555

10406-086EA 811.1 USD

10406-086

Anti-G6PDH Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Antibodies

Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) . Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: Glucose 6 Phosphate Dehydrogenase
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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