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Anti-CSPG4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200

Type: Primary
Antigen: CSPG4
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype:
Reactivity:




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-4800R-A488 10398-830 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CSPG4
Antigen Name Chondroitin sulfate proteoglycan 4
Reactivity Mouse, Rat, Human
Conjugation Alexa Fluor® 488
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Flow Cytometry Yes
Antigen Synonyms HMW-MAA, NG2, MEL-CSPG, MSK16, MCSP, MCSPG
Gene ID 1464
Concentration 1 μg/μl
Cross Adsorption No
Immunogen 730-780/2322
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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