Anti-H3F3A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss

BS-3776R-A555

10394-836EA 811.1 USD

10394-836

Anti-H3F3A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Antibodies

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: Histone H3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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