Anti-P53 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

BS-3711R-A488
10396-086EA 811.12 USD
10396-086
Anti-P53 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: P53
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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