Anti-KEAP1 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

BS-3648R-CY5
10375-842EA 811.1 USD
10375-842
Anti-KEAP1 Rabbit Polyclonal Antibody (Cy5®)
Antibodies
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: KEAP1
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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