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Anti-TNK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Supplier: Bioss

BS-3587R-FITC

10373-640EA 811.1 USD

10373-640

Anti-TNK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Antibodies

Tnk1 is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TNK1
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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