Anti-ZAP70 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

BS-3479R-A488
10372-840EA 811.12 USD
10372-840
Anti-ZAP70 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ZAP70
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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