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Anti-SYK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-3433R-A647

10369-030EA 746.43 USD

10369-030

Anti-SYK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Antibodies

Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk; Spleen tyrosine kinase; Tyrosine protein kinase SYK.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: SYK
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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