Anti-STAT2 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

BS-3428R-CY7
10368-968EA 811.12 USD
10368-968
Anti-STAT2 Rabbit Polyclonal Antibody (Cy7®)
Antibodies
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: STAT2
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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