Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

10368-544EA 776.19 USD
Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: INPPL1
Clonality: Polyclonal
Conjugation: Alexa Fluor® 350
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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