Anti-ARAF Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

10368-158EA 776.19 USD
Anti-ARAF Rabbit Polyclonal Antibody (Cy7®)
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ARAF
Clonality: Polyclonal
Conjugation: Cy7®
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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