Anti-PIN1 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss

BS-3354R-CY5.5

10367-844EA 776.19 USD

10367-844

Anti-PIN1 Rabbit Polyclonal Antibody (Cy5.5®)

Antibodies

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PIN1
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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